| 产品名称 | IMM 01 |
| 产品货号 | Axon 2406 CAS [218795-74-5] MF C12H17N3O2SMW 267.35 Purity: 99% Soluble in DMSO Description Small-molecule agonist of mammalian Diaphanous (mDia)-related formins that inhibited DID–DAD binding (IC50 value 140 nM). IMM-01 induced filopodia-like structures similar to those observed in cells expressing constitutively active mDia1 or mDia2. Moreover, IMM01 triggered actin assembly and microtubule stabilization consistent with formin activation in NIH 3T3 cells. References Certificates Categories Extra info L.L. Lash et al. Small-molecule intramimics of formin autoinhibition: a new strategy to target the cytoskeletal remodeling machinery in cancer cells. Cancer Res. 2013 Nov 15;73(22):6793-803. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Immunology mDia Small-molecule agonist of mammalian Diaphanous (mDia)-related formins Chemical name N-tert-butyl-2-(2,4-dihydroxybenzylidene)hydrazinecarbothioamide Parent CAS No. [218795-74-5] Order Size Unit Price Stock 10 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
IMM 01Axon 2406 CAS [218795-74-5] MF C12H17N3O2S
Description
Small-molecule agonist of mammalian Diaphanous (mDia)-related formins that inhibited DID–DAD binding (IC50 value 140 nM). IMM-01 induced filopodia-like structures similar to those observed in cells expressing constitutively active mDia1 or mDia2. Moreover, IMM01 triggered actin assembly and microtubule stabilization consistent with formin activation in NIH 3T3 cells.
Small-molecule agonist of mammalian Diaphanous (mDia)-related formins
Chemical nameN-tert-butyl-2-(2,4-dihydroxybenzylidene)hydrazinecarbothioamide Parent CAS No.[218795-74-5] |
| 产品资料 |
