| 产品名称 | TH 1834 |
| 产品货号 | Axon 2339 CAS [N.A.] MF C33H40N6O3.2HClMW 641.63 Purity: 99% Soluble in water and DMSO Description Tip60 histone acetyltransferase inhibitor. Treating cells with TH1834 results in apoptosis and increased unrepaired DNA damage (following ionizing radiation treatment) in breast cancer but not control cell lines. Furthermore, TH 1834 did not affect the activity of related HAT MOF, as indicated by H4K16Ac, demonstrating specificity. References Certificates Categories Extra info C. Gao et al. Rational design and validation of a Tip60 histone acetyltransferase inhibitor. Sci. Rep. 2014, 4, 5372. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics HAT Transcription Factors p53-Tumor Suppression Wnt-β-Catenin NF-κB JAK-STAT DNA-damage Response EC 2.3.1.48 Tip60 histone acetyltransferase inhibitor Chemical name 2-(5-(4-((phenethyl(4-(4-(pyrrolidin-1-ylmethyl)phenoxy)butyl)amino)methyl)phenyl)-2H-tetrazol-2-yl)acetic acid dihydrochloride Parent CAS No. [N.A.] Order Size Unit Price Stock 5 mg €135.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
TH 1834Axon 2339 CAS [N.A.] MF C33H40N6O3.2HCl
DescriptionTip60 histone acetyltransferase inhibitor. Treating cells with TH1834 results in apoptosis and increased unrepaired DNA damage (following ionizing radiation treatment) in breast cancer but not control cell lines. Furthermore, TH 1834 did not affect the activity of related HAT MOF, as indicated by H4K16Ac, demonstrating specificity.
Tip60 histone acetyltransferase inhibitor
Chemical name2-(5-(4-((phenethyl(4-(4-(pyrrolidin-1-ylmethyl)phenoxy)butyl)amino)methyl)phenyl)-2H-tetrazol-2-yl)acetic acid dihydrochloride Parent CAS No.[N.A.] |
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