产品名称 CXCR3 Antagonist 6c - Compound 6c
产品货号 Axon 1800 CAS [870998-13-3] MF C30H32Cl3N5O3MW 616.97 Purity: 99% Soluble in DMSO Description Potent chemokine CXCR3 antagonist, exhibiting IC50 value of 60 nM in a calcium mobilization functional assay; dose-dependently inhibiting CXCR3 functional response to CXCL11 as measured by T-cell chemotaxis, with a potency of about 100 nM References Certificates Categories Extra info AG Cole et al. Identification and initial evaluation of 4-N-aryl-[1,4]diazepane ureas as potent CXCR3 antagonists. Bioorg. Med. Chem. Let. 2006, 16(1), 200-203. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Immunology A1 Chemokine CXCR3 antagonist Chemical name 4-(2-(3-chlorobenzamido)-4-(2,4-dichlorophenethylcarbamoyl)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide Parent CAS No. [870998-13-3] Order Size Unit Price Stock 10 mg €135.00 In Stock
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CXCR3 Antagonist 6c - Compound 6c

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1800

CAS [870998-13-3]

MF C30H32Cl3N5O3
MW 616.97

  • Purity: 99%
  • Soluble in DMSO

CXCR3 Antagonist 6c

Description

Potent chemokine CXCR3 antagonist, exhibiting IC50 value of 60 nM in a calcium mobilization functional assay; dose-dependently inhibiting CXCR3 functional response to CXCL11 as measured by T-cell chemotaxis, with a potency of about 100 nM
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