产品名称 | CXCR3 Antagonist 6c - Compound 6c |
产品货号 | Axon 1800 CAS [870998-13-3] MF C30H32Cl3N5O3MW 616.97 Purity: 99% Soluble in DMSO Description Potent chemokine CXCR3 antagonist, exhibiting IC50 value of 60 nM in a calcium mobilization functional assay; dose-dependently inhibiting CXCR3 functional response to CXCL11 as measured by T-cell chemotaxis, with a potency of about 100 nM References Certificates Categories Extra info AG Cole et al. Identification and initial evaluation of 4-N-aryl-[1,4]diazepane ureas as potent CXCR3 antagonists. Bioorg. Med. Chem. Let. 2006, 16(1), 200-203. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Immunology A1 Chemokine CXCR3 antagonist Chemical name 4-(2-(3-chlorobenzamido)-4-(2,4-dichlorophenethylcarbamoyl)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide Parent CAS No. [870998-13-3] Order Size Unit Price Stock 10 mg €135.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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CXCR3 Antagonist 6c - Compound 6cAxon 1800 CAS [870998-13-3] MF C30H32Cl3N5O3
Description
Potent chemokine CXCR3 antagonist, exhibiting IC50 value of 60 nM in a calcium mobilization functional assay; dose-dependently inhibiting CXCR3 functional response to CXCL11 as measured by T-cell chemotaxis, with a potency of about 100 nM
CXCR3 antagonist
Chemical name4-(2-(3-chlorobenzamido)-4-(2,4-dichlorophenethylcarbamoyl)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide Parent CAS No.[870998-13-3] |
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