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产品名称 Abiraterone acetate - CB 7630 | JNJ 212082
产品货号 Axon 1874 CAS [154229-18-2] MF C26H33NO2MW 391.55 Purity: 100% Optical purity: Optically pure Poorly soluble in DMSO Description Orally administered prodrug of Abiraterone (Axon 1873); inhibitor of the steroidal enzyme 17 α-hydroxylase/C17,20 lyase (CYP17A1); a drug used in castration-resistant prostate cancer (CRPC) References Certificates Categories Extra info G Attard et al. Selective blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer. BJU Int. 2005, 96 (9), 1241–1246.    JE Ang et al. CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer. Br. J. Cancer 2009, 100(5), 671–675.  Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Diabetes & Metabolism Endocrinology EC 1.14.99.9 Cytochrome P450 Prodrug of Abiraterone; Inhibitor of CYP17A1 Chemical name (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate Parent CAS No. [154229-18-2] Order Size Unit Price Stock 10 mg €90.00 In Stock
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Abiraterone acetate - CB 7630 | JNJ 212082

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1874

CAS [154229-18-2]

MF C26H33NO2
MW 391.55

  • Purity: 100%
  • Optical purity: Optically pure
  • Poorly soluble in DMSO

Abiraterone acetate

Description

Orally administered prodrug of Abiraterone (Axon 1873); inhibitor of the steroidal enzyme 17 α-hydroxylase/C17,20 lyase (CYP17A1); a drug used in castration-resistant prostate cancer (CRPC)
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