产品名称

SB 265610

产品货号

Axon 1559 CAS [ 211096-49-0] MF C14H9BrN6OMW 357.16 Purity: 99% Soluble in DMSO Description Potent allosteric, inverse agonist/antagonist at the human chemokine CXCR2 receptor. SB-265610 antagonizes rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization, and rat neutrophil chemotaxis in a concentration-dependent manner (IC50 values 3.7 nM and 70 nM, respectively). KEYWORDS: SB 265610 | supplier | CXCR2 antagonist | SB265610 | CAS [ 211096-49-0] | Chemokine | Inverse agonist | Antagonist | C-X-C | neutrophil | chemotaxis | calcium mobilization | GPCR

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

SB 265610

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1559

CAS [ 211096-49-0]

MF C14H9BrN6O
MW 357.16

Purity: 99%
Soluble in DMSO

SB 265610

Description

Potent allosteric, inverse agonist/antagonist at the human chemokine CXCR2 receptor. SB-265610 antagonizes rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization, and rat neutrophil chemotaxis in a concentration-dependent manner (IC50 values 3.7 nM and 70 nM, respectively).