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产品名称 PF 05081090 - PF 5081090
产品货号 Axon 2113 CAS [1312473-63-4] MF C18H21FN2O6SMW 412.43 Purity: 98% Optical purity: Optically pure Soluble in DMSO Description Very potent antibacterial LpxC inhibitor for the treatment of serious gram-negative infections (Pseudomonas aeruginosa (Pae) enzyme potency (Pae IC50) of 1.1 nM) References Certificates Categories Extra info JI Montgomery et al. Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections. J. Med. Chem. 2012, 55(4), 1662-1670.     MF Brown et al. Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections. J. Med. Chem. 2012, 55(2), 914–923.   Certificate of Analysis Material Safety Data Sheet Immunology LpxC EC 3.5.1.108 Pfizer Licensed Products Antibiotics LpxC inhibitor for treatment of gram-negative infections Chemical name (R)-4-(4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [1312473-63-4] Order Size Unit Price Stock 5 mg €95.00 In Stock
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PF 05081090 - PF 5081090

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2113

CAS [1312473-63-4]

MF C18H21FN2O6S
MW 412.43

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in DMSO

PF 05081090

Description

Very potent antibacterial LpxC inhibitor for the treatment of serious gram-negative infections (Pseudomonas aeruginosa (Pae) enzyme potency (Pae IC50) of 1.1 nM)
LpxC inhibitor for treatment of gram-negative infections

Chemical name

(R)-4-(4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[1312473-63-4]
产品资料