产品名称 Linezolid - Zyvox | PNU 100766 | U 100766
产品货号 Axon 2048 CAS [165800-03-3] MF C16H20FN3O4MW 337.35 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Protein synthesis inhibitor; antibiotic; stops the growth of bacteria by disrupting their production of proteins; inhibits the ribosomal peptidyltransferase; antibacterial agent for the treatment of multidrug-resistant gram-positive bacterial infections References Certificates Categories Extra info SJ Brickner et al. Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections. J. Med. Chem. 2008, 51(7), 1981-1990.   MR Barbachyn, CW Ford. Oxazolidinone structure-activity relationships leading to linezolid. Angew. Chem. Int. Ed. Engl. 2003, 42(18), 2010-23.     SJ Brickner et al. Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections. J. Med. Chem. 1996, 39(3), 673-9.   U Patel et al. Oxazolidinones mechanism of action: inhibition of the first peptide bond formation. J. Biol. Chem. 2001, 276(40), 37199-205.    CE Barry and JS Blanchard. The Chemical Biology of New Drugs in Development for Tuberculosis. Curr. Opin. Chem. Biol. 2010, 14(4), 456–466.  Certificate of Analysis Material Safety Data Sheet Immunology EC 2.3.2.12 Peptidyl Transferase Pfizer Licensed Products Antibiotics Protein synthesis inhibitor; antibiotic Chemical name (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [165800-03-3] Order Size Unit Price Stock 10 mg €85.00 In Stock
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Linezolid - Zyvox | PNU 100766 | U 100766

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2048

CAS [165800-03-3]

MF C16H20FN3O4
MW 337.35

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO

Linezolid

Description

Protein synthesis inhibitor; antibiotic; stops the growth of bacteria by disrupting their production of proteins; inhibits the ribosomal peptidyltransferase; antibacterial agent for the treatment of multidrug-resistant gram-positive bacterial infections
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