产品名称 | MGL-3196 - VIA-3196 |
产品货号 | Axon 2657 CAS [920509-32-6] MF C17H12Cl2N6O4MW 435.22 Purity: 99% Soluble in DMSO Description Oral, liver-targeted, selective thyroid hormone receptor β-agonist (EC50 value 0.21 µM for THR-β) that is being developed for the treatment of dyslipidemia. MGL-3196 is 28-fold selective for THR-β over THR-α in an in vitro functional coactivator recruitment assay. KEYWORDS: MGL-3196 | supplier | THR-β agonist | VIA-3196 | MGL3196 | VIA3196 | CAS [920509-32-6] | Triiodothyronine | thyroid hormone receptor | THR | NR1A | nuclear receptor | dyslipidemia | HDL | LDL | cholesterol | cardiovascular | diabetes | hypercholesterolemic |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
产品概述 | |
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MGL-3196 - VIA-3196Axon 2657 CAS [920509-32-6] MF C17H12Cl2N6O4
DescriptionOral, liver-targeted, selective thyroid hormone receptor β-agonist (EC50 value 0.21 µM for THR-β) that is being developed for the treatment of dyslipidemia. MGL-3196 is 28-fold selective for THR-β over THR-α in an in vitro functional coactivator recruitment assay. KEYWORDS: MGL-3196 | supplier | THR-β agonist | VIA-3196 | MGL3196 | VIA3196 | CAS [920509-32-6] | Triiodothyronine | thyroid hormone receptor | THR | NR1A | nuclear receptor | dyslipidemia | HDL | LDL | cholesterol | cardiovascular | diabetes | hypercholesterolemic
Oral, liver-targeted, selective thyroid hormone receptor β-agonist
Chemical name2-(3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile Parent CAS No.[920509-32-6] |
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