| 产品名称 | Celecoxib - SC 58635 | Celebrex | Celebra |
| 产品货号 | Axon 1919 CAS [169590-42-5] MF C17H14F3N3O2SMW 381.37 Purity: 99% Soluble in DMSO Description Selective cyclooxygenase-2 (COX-2) inhibitor (IC50: 15 and 0.04 μM for COX-1 and COX-2 respectively); inhibition of COX-2 inhibits only prostaglandin synthesis without affecting thromboxane (TXA2) and thus offers no cardioprotective effects of NSAIDs, which inhibits both COX-1 and COX-2 non-selectively. References Certificates Categories Extra info TD Penning et al. Synthesis and Biological Evaluation of the 1.5 Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole-(...). J. Med. Chem. 1997, 40 (9), 1347–1365. DL DeWitt. Cox-2-selective inhibitors: the new super aspirins. Mol. Pharmacol. 1999, 55(4), 625-631. Certificate of Analysis Material Safety Data Sheet CNS Immunology Pain & Inflammation EC 1.14.99.1 COX Pfizer Licensed Products Selective COX-2 inhibitor Chemical name 4-(5-p-tolyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [169590-42-5] Order Size Unit Price Stock 10 mg €50.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
Celecoxib - SC 58635 | Celebrex | CelebraAxon 1919 CAS [169590-42-5] MF C17H14F3N3O2S
Description
Selective cyclooxygenase-2 (COX-2) inhibitor (IC50: 15 and 0.04 μM for COX-1 and COX-2 respectively); inhibition of COX-2 inhibits only prostaglandin synthesis without affecting thromboxane (TXA2) and thus offers no cardioprotective effects of NSAIDs, which inhibits both COX-1 and COX-2 non-selectively.
Selective COX-2 inhibitor
Chemical name4-(5-p-tolyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[169590-42-5] |
| 产品资料 |
