产品名称

ATB 346

产品货号

Axon 2288 CAS [1226895-20-0] MF C21H19NO3SMW 365.45 Purity: 99% Soluble in DMSO Description Orally active hydrogen sulfide-releasing cyclooxygenase inhibitor and a derivative of Naproxen (significantly reduced exudate leukocyte and PGE2 levels at 30 µmol/kg oral administration). ATB-346 exhibits anti-inflammatory properties similar to naproxen.In a mouse airpouch model, ATB-346 suppressed cyclooxygenase-2 activity and inhibited leukocyte infiltration more effectively than naproxen but with substantially reduced gastrointestinal toxicity (100-fold safer than naproxen). KEYWORDS: ATB 346 | supplier | COX inhibitor; H2S-releasing compound | ATB346 | CAS [1226895-20-0] | Fatty acid (Arachidonic acid) | COX | Inhibitor | cyclooxygenase | Naproxen | anti-inflammatory | leukocyte infiltration

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

ATB 346

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2288

CAS [1226895-20-0]

MF C21H19NO3S
MW 365.45

Purity: 99%
Soluble in DMSO

ATB 346

Description

Orally active hydrogen sulfide-releasing cyclooxygenase inhibitor and a derivative of Naproxen (significantly reduced exudate leukocyte and PGE2 levels at 30 µmol/kg oral administration). ATB-346 exhibits anti-inflammatory properties similar to naproxen.In a mouse airpouch model, ATB-346 suppressed cyclooxygenase-2 activity and inhibited leukocyte infiltration more effectively than naproxen but with substantially reduced gastrointestinal toxicity (100-fold safer than naproxen).