产品名称

Boc-D-FMK - Boc-Asp(OMe)-fluoromethyl ketone | BAF

产品货号

Axon 2158 CAS [187389-53-3] MF C11H18FNO5MW 263.26 Purity: 98% Optical purity: Optically pure Soluble in water and DMSO Description Broad spectrum caspase inhibitor. Causes concentration-dependent inhibition of only TNFα-stimulated apoptosis (IC50 value 39 μM). Boc-D-FMK could significantly promote the survival of spinal motoneurons after root avulsion in neonates, but not in adult rats. Boc-D-FMK treatment reduces acute cell death after traumatic brain injury (TBI) by inhibiting mitochondrial release of cytochrome c, possibly via a mechanism involving initiator caspases-2, and -3-like, but not -8). KEYWORS: Boc-D-FMK | supplier | Caspase inhibitor | apoptosis | TNF | boc-Aspartyl(OMe)-fluoromethylketone | BAF | traumatic | Brain injury | TBI | survival | motoneurons

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Boc-D-FMK - Boc-Asp(OMe)-fluoromethyl ketone | BAF

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2158

CAS [187389-53-3]

MF C11H18FNO5
MW 263.26

Purity: 98%
Optical purity: Optically pure
Soluble in water and DMSO

Boc-D-FMK

Description

Broad spectrum caspase inhibitor. Causes concentration-dependent inhibition of only TNFα-stimulated apoptosis (IC50 value 39 μM). Boc-D-FMK could significantly promote the survival of spinal motoneurons after root avulsion in neonates, but not in adult rats. Boc-D-FMK treatment reduces acute cell death after traumatic brain injury (TBI) by inhibiting mitochondrial release of cytochrome c, possibly via a mechanism involving initiator caspases-2, and -3-like, but not -8).