产品名称 APPA
产品货号 Axon 2883 CAS [100750-39-8] MF C14H13NO3MW 243.26 Purity: 99% Soluble in DMSO Recently added
产品价格 现货询价,电话:010-67529703
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产品品牌 axonmedchem
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APPA

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2883

CAS [100750-39-8]

MF C14H13NO3
MW 243.26

  • Purity: 99%
  • Soluble in DMSO
Recently added

APPA

Description

APPA is an aldose reductase inhibitor with an IC50 value of 0.0223 μM. APPA could inhibit apoptosis in rat glomerular mesangial cells in vitro. In addition, APPA improved the pathological symptoms of streptozotocin-induced diabetic nephropathy (DN) in rats by affecting antioxidant activities and reducing the levels of TGF-β, collagen IV, and laminin.

KEYWORDS: APPA | supplier | Aldose reductase inhibitor | CAS [100750-39-8] | Aldose | Aldose reductase | Inhibitor | Enzymes | Diabetic Nephropathy | Diabetes Mellitus | Polyol Pathway

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