产品名称

Iniparib - BSI 201

产品货号

Axon 1566 CAS [160003-66-7] MF C7H5IN2O3MW 292.03 Purity: 99% Soluble in DMSO Description An irreversible inhibitor of poly(ADP-ribose) polymerase-1 (PARP 1); it inhibits PARP1, a nuclear enzyme that promotes DNA repair through the base-excision repair pathway; potential therapeutic undergoing clinical trials for treatment of some types of breast cancer References Certificates Categories Extra info A Patel and SH Kaufmann. Development of PARP Inhibitors: An Unfinished Story. ONCOLOGY. 2010, Vol. 24 No. 1. J O'Shaughnessy et al. Iniparib plus Chemotherapy in Metastatic Triple-Negative Breast Cancer. N. Engl. J. Med. 2011, 364, 205-214. LA Carey and NE Sharpless. PARP and Cancer — If It's Broke, Don't Fix It. N. Engl. J. Med. 2011, 364, 277-279. Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 2.4.2.30 PARP PARP inhibitor Chemical name 4-iodo-3-nitrobenzamide Parent CAS No. [160003-66-7] Order Size Unit Price Stock 10 mg €65.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Iniparib - BSI 201

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1566

CAS [160003-66-7]

MF C7H5IN2O3
MW 292.03

Purity: 99%
Soluble in DMSO

Iniparib

Description

An irreversible inhibitor of poly(ADP-ribose) polymerase-1 (PARP 1); it inhibits PARP1, a nuclear enzyme that promotes DNA repair through the base-excision repair pathway; potential therapeutic undergoing clinical trials for treatment of some types of breast cancer