产品名称 AZD 2281 - Olaparib | KU 0059436
产品货号 Axon 1464 CAS [763113-22-0] MF C24H23FN4O3MW 434.46 Purity: 99% Soluble in DMSO Description Highly potent, oral and selective inhibitor of poly(ADP-ribose) polymerase (PARP); with IC50 = 5nM (PARP-1) and 1 nM (PARP-2). It blocks enzymes that repair DNA damage caused by cancer treatments such as radiation and drugs. KEYWORDS: AZD 2281 | supplier | PARP inhibitor | Olaparib | KU 0059436 | AZD2281 | KU0059436 | AZD-2281 | KU-0059436 | CAS [763113-22-0] | DNA-RNA | poly-(ADP-ribose) polymerase | PARP-1 | PARP-2 | DNA damage | double strand break | DSB | CHK
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产品品牌 axonmedchem
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AZD 2281 - Olaparib | KU 0059436

Based on 1690 reference(s) in Google Scholar 9 10 1690

Axon 1464

CAS [763113-22-0]

MF C24H23FN4O3
MW 434.46

  • Purity: 99%
  • Soluble in DMSO

AZD 2281

Description

Highly potent, oral and selective inhibitor of poly(ADP-ribose) polymerase (PARP); with IC50 = 5nM (PARP-1) and 1 nM (PARP-2). It blocks enzymes that repair DNA damage caused by cancer treatments such as radiation and drugs.

KEYWORDS: AZD 2281 | supplier | PARP inhibitor | Olaparib | KU 0059436 | AZD2281 | KU0059436 | AZD-2281 | KU-0059436 | CAS [763113-22-0] | DNA-RNA | poly-(ADP-ribose) polymerase | PARP-1 | PARP-2 | DNA damage | double strand break | DSB | CHK

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