产品名称

ME0328

产品货号

Axon 2759 CAS [1445251-22-8] MF C19H19N3O2MW 321.37 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description ME0328 is a potent, cell-permeable, selective inhibitor of PARP3/ARTD3 (IC50 value of 0.9 μM). KEYWORDS: ME0328 | supplier | PARP inhibitor | ME 0328 | ME-0328 | CAS [1445251-22-8] | DNA-RNA | PARP | Inhibitor | Enzymes | ARTD3 | PARP3

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

ME0328

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2759

CAS [1445251-22-8]

MF C19H19N3O2
MW 321.37

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

ME0328

Description

ME0328 is a potent, cell-permeable, selective inhibitor of PARP3/ARTD3 (IC50 value of 0.9 μM).

KEYWORDS: ME0328 | supplier | PARP inhibitor | ME 0328 | ME-0328 | CAS [1445251-22-8] | DNA-RNA | PARP | Inhibitor | Enzymes | ARTD3 | PARP3

AE Lindgren et al. Chemical probes to study ADP-ribosylation: synthesis and biochemical evaluation of inhibitors of the human ADP-ribosyltransferase ARTD3/PARP3. J Med Chem. 2013 Dec 12;56(23):9556-68.

AE Lindgren et al. PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3. ACS Chem Biol. 2013 Aug 16;8(8):1698-703.

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 2.4.2.30 PARP

PARP3/ARTD3 inhibitor

Chemical name

(S)-3-(4-Oxo-3,4-dihydroquinazolin-2-yl)-N-(1-phenylethyl)propanamide

Parent CAS No.

[1445251-22-8]

产品资料