产品名称 | Atglistatin |
产品货号 | Axon 2276 CAS [1469924-27-3] MF C17H21N3OMW 283.37 Purity: 98% Soluble in DMSO Description Highly potent and selective inhibitor of adipose triglyceride lipase (ATGL; IC50 value 0.7 μM) that reduces fatty acid mobilization in vitro and in vitro. Atglistatin does not inhibit HSL, monoglyceride lipase, pancreatic lipase, lipoprotein lipase and two lysophospholipases of the patatin-like phospholipase domain–containing protein family (PNPLA) exhibiting homology to ATGL. References Certificates Categories Extra info N. Mayer et al. Development of small-molecule inhibitors targeting adipose triglyceride lipase. Nat. Chem. Biol. 2013, 9, 785-787. Certificate of Analysis Material Safety Data Sheet Cardiovascular Diabetes & Metabolism ATGL EC 3.1.1.3 Potent and selective inhibitor of adipose triglyceride lipase (ATGL) Chemical name 3-(4'-(dimethylamino)biphenyl-3-yl)-1,1-dimethylurea Parent CAS No. [1469924-27-3] Order Size Unit Price Stock 5 mg €90.00 In Stock |
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产品品牌 | axonmedchem |
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AtglistatinAxon 2276 CAS [1469924-27-3] MF C17H21N3O
Description
Highly potent and selective inhibitor of adipose triglyceride lipase (ATGL; IC50 value 0.7 μM) that reduces fatty acid mobilization in vitro and in vitro.
Atglistatin does not inhibit HSL, monoglyceride lipase, pancreatic lipase, lipoprotein lipase and two lysophospholipases of the patatin-like phospholipase domain–containing protein family (PNPLA) exhibiting homology to ATGL.
Potent and selective inhibitor of adipose triglyceride lipase (ATGL)
Chemical name3-(4'-(dimethylamino)biphenyl-3-yl)-1,1-dimethylurea Parent CAS No.[1469924-27-3] |
产品资料 |