产品名称

MJN110

产品货号

Axon 2580 CAS [1438416-21-7] MF C22H21Cl2N3O4MW 462.33 Purity: 98% Soluble in DMSO Description Potent, selective, and in-vivo-active MAGL inhibitor (IC50 values 9.5 nM and 260 nM for inhibition of mouse MAGL and ABHD6, respectively) displaying strong antihyperalgesic activity (mechanical allodynia) in a rat model of diabetic neuropathy. MJN110 exhibits therapeutic potential in the treatment of acute nausea and vomiting as well as anticipatory nausea by elevation of endogenous cannabinoid 2-arachidonoylglycerol (2-AG) levels in the brain. KEYWORDS: MJN110 | supplier | MAGL inhibitor | MJN-110 | CAS [1438416-21-7] | 2-arachidonoyl glycerol | 2-AG | MAGL | Inhibitor | endo-cannabinoid | ABHD6 | antihyperalgesic | allodynia | diabetic neuropathy | nausea | vomiting

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

MJN110

Based on 56 reference(s) in Google Scholar 9 10 56

Axon 2580

CAS [1438416-21-7]

MF C22H21Cl2N3O4
MW 462.33

Purity: 98%
Soluble in DMSO

MJN110

Description

Potent, selective, and in-vivo-active MAGL inhibitor (IC50 values 9.5 nM and 260 nM for inhibition of mouse MAGL and ABHD6, respectively) displaying strong antihyperalgesic activity (mechanical allodynia) in a rat model of diabetic neuropathy. MJN110 exhibits therapeutic potential in the treatment of acute nausea and vomiting as well as anticipatory nausea by elevation of endogenous cannabinoid 2-arachidonoylglycerol (2-AG) levels in the brain.