产品名称 | Atorvastatin calcium - Lipitor |
产品货号 | Axon 2043 CAS [134523-03-8] MF C33H34FN2O5.½CaMW 577.67 Purity: 99% Soluble in DMSO Description An inhibitor of HMG-CoA reductase (statin) indicated as an adjunct therapy to diet to lower the LDL ("bad") cholesterol and triglycerides in your blood. It can raise your HDL ("good") cholesterol as well. References Certificates Categories Extra info BD Roth. The Discovery and Development of Atorvastatin, a Potent Novel Hypolipidemic Agent. Prog. Med. Chem. 2002, 40, 1–22. S Youssef et al. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature 2002, 420, 78-84. HM Colhoun et al. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet, 2004, 364 (9435), 685 - 696. PS Sever et al. Prevention of Coronary and Stroke Events with Atorvastatin in Hypertensive Patients who have Average or Lower-than-Average Cholesterol Concentrations, in the Anglo-Scandinavian Cardiac (...). Drugs 2004, 64 (2 Suppl.), 43-60. JC LaRosa et al. Intensive Lipid Lowering with Atorvastatin in Patients with Stable Coronary Disease. N. Engl. J. Med. 2005, 352, 1425-1435. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Diabetes & Metabolism HMG-CoA reductase EC 1.1.1.88 Pfizer Licensed Products Inhibitor of HMG-CoA reductase Chemical name (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate hemi-calcium salt Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [134523-00-5] Order Size Unit Price Stock 10 mg €70.00 In Stock |
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产品品牌 | axonmedchem |
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Atorvastatin calcium - LipitorAxon 2043 CAS [134523-03-8] MF C33H34FN2O5.½Ca
Description
An inhibitor of HMG-CoA reductase (statin) indicated as an adjunct therapy to diet to lower the LDL ("bad") cholesterol and triglycerides in your blood. It can raise your HDL ("good") cholesterol as well.
Inhibitor of HMG-CoA reductase
Chemical name(3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate hemi-calcium salt Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[134523-00-5] |
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