产品名称 AB 1010 - Masitinib mesylate
产品货号 Axon 1419 CAS [1048007-93-7] MF C28H30N6OS.CH4O3SMW 594.75 Purity: 99% Soluble in water and DMSO Description A potent oral tyrosine kinase inhibitor, targeting c-KIT, PDGFR and FGFR3; oncology drug under clinical trial References Certificates Categories Extra info P Dubreuil et al. Masitinib (AB1010), a Potent and Selective Tyrosine Kinase Inhibitor Targeting KIT. Plos ONE 2009, 4(9), e7258.    BN Bui et al. Preliminary efficacy and safety results of masitinib administered, front line in patients with advanced GIST. A phase II study. J. Clin. Onco. 2007, 25(18S), 10025.    G Giamas et al. Protein kinases as targets for cancer treatment. Pharmacogenomics. 2007, 8(8), 1005-1016.    KA Hahn et al. Masitinib is safe and effective for the treatment of canine mast cell tumors. J. Vet. Intern. Med. 2008, 22(6), 1301-1309.  Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology PDGFR c-KIT RTK class III and V; EC 2.7.10.1 FGFR PDGFR, c-KIT and FGFR3 tyrosine kinase inhibitor Chemical name 4-(4-Methyl-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-thiazol-2-ylamino)-phenyl]-benzamide methanesulfonate Parent CAS No. [790299-79-5] Order Size Unit Price Stock 5 mg €70.00 In Stock
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AB 1010 - Masitinib mesylate

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1419

CAS [1048007-93-7]

MF C28H30N6OS.CH4O3S
MW 594.75

  • Purity: 99%
  • Soluble in water and DMSO

AB 1010

Description

A potent oral tyrosine kinase inhibitor, targeting c-KIT, PDGFR and FGFR3; oncology drug under clinical trial
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