产品名称 | CT 53518 - MLN 518 | Tandutinib |
产品货号 | Axon 1415 CAS [387867-13-2] MF C31H42N6O4MW 562.70 Purity: 99% Soluble in DMSO Description An oral tyrosine kinase inhibitor (TKI), targeting FLT3 (FMS-Like Tyrosine kinase-3), c-KIT and PDGFR, thereby inhibiting cellular proliferation and inducing apoptosis. References Certificates Categories Extra info L Kelly et al. CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML). Cancer Cell , 2003, 1(5), 421 - 432. [online abstract] IJ Griswold et al. Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis. Blood 2004, 104(9), 2912-8. [online abstract] Certificate of Analysis Material Safety Data Sheet Angiogenesis Apoptosis Cell Signaling & Oncology FLT3 PDGFR c-KIT RTK class III; EC 2.7.10.1 PDGFR, c-KIT and FLT3 tyrosine kinase inhibitor Chemical name 4-[7-(3-Piperidin-1-yl-propoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide Parent CAS No. [387867-13-2] Order Size Unit Price Stock 5 mg €75.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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CT 53518 - MLN 518 | TandutinibAxon 1415 CAS [387867-13-2] MF C31H42N6O4
Description
An oral tyrosine kinase inhibitor (TKI), targeting FLT3 (FMS-Like Tyrosine kinase-3), c-KIT and PDGFR, thereby inhibiting cellular proliferation and inducing apoptosis.
PDGFR, c-KIT and FLT3 tyrosine kinase inhibitor
Chemical name4-[7-(3-Piperidin-1-yl-propoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide Parent CAS No.[387867-13-2] |
产品资料 |