产品名称 CT 53518 - MLN 518 | Tandutinib
产品货号 Axon 1415 CAS [387867-13-2] MF C31H42N6O4MW 562.70 Purity: 99% Soluble in DMSO Description An oral tyrosine kinase inhibitor (TKI), targeting FLT3 (FMS-Like Tyrosine kinase-3), c-KIT and PDGFR, thereby inhibiting cellular proliferation and inducing apoptosis. References Certificates Categories Extra info L Kelly et al. CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML). Cancer Cell , 2003, 1(5), 421 - 432. [online abstract]   IJ Griswold et al. Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis. Blood 2004, 104(9), 2912-8. [online abstract] Certificate of Analysis Material Safety Data Sheet Angiogenesis Apoptosis Cell Signaling & Oncology FLT3 PDGFR c-KIT RTK class III; EC 2.7.10.1 PDGFR, c-KIT and FLT3 tyrosine kinase inhibitor Chemical name 4-[7-(3-Piperidin-1-yl-propoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide Parent CAS No. [387867-13-2] Order Size Unit Price Stock 5 mg €75.00 In Stock
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CT 53518 - MLN 518 | Tandutinib

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1415

CAS [387867-13-2]

MF C31H42N6O4
MW 562.70

  • Purity: 99%
  • Soluble in DMSO

CT 53518

Description

An oral tyrosine kinase inhibitor (TKI), targeting FLT3 (FMS-Like Tyrosine kinase-3), c-KIT and PDGFR, thereby inhibiting cellular proliferation and inducing apoptosis.
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