| 产品名称 | PF 04217903 mesylate |
| 产品货号 | Axon 1583 CAS [956906-93-7] MF C19H16N8O.CH4O3SMW 468.49 Purity: 99% Soluble in 0.1N HCl(aq) Description An orally bioavailabe tyrosine kinase inhibitor, targeting MET (or c-MET); it selectively binds to and inhibits mesenchymal epithelial transition (low nM Ki values and >1000 fold selective relative to 208 kinases) with potential antineoplastic activity References Certificates Categories Extra info SL Timofeevski et al. Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors. Biochemistry. 2009, 48(23), 5339-49. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology c-MET RTK class X; EC 2.7.10.1 c-MET tyrosine kinase Inhibitor Chemical name 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol methanesulfonate Parent CAS No. [956905-27-4] Order Size Unit Price Stock 5 mg €80.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
PF 04217903 mesylateAxon 1583 CAS [956906-93-7] MF C19H16N8O.CH4O3S
Description
An orally bioavailabe tyrosine kinase inhibitor, targeting MET (or c-MET); it selectively binds to and inhibits mesenchymal epithelial transition (low nM Ki values and >1000 fold selective relative to 208 kinases) with potential antineoplastic activity
c-MET tyrosine kinase Inhibitor
Chemical name2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol methanesulfonate Parent CAS No.[956905-27-4] |
| 产品资料 |
