| 产品名称 | SU 11274 |
| 产品货号 | Axon 1581 CAS [658084-23-2] MF C28H30ClN5O4SMW 568.09 Purity: 99% Soluble in DMSO Description ATP-competitive and selective MET inhibitor; inhibition of the Met kinase activity by SU11274 led to time- and dose-dependent reduced cell growth and induced G1 cell cycle arrest and apoptosis References Certificates Categories Extra info S Berthou et al. The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants. Oncogene 2004, 23, 5387-5393. PC Ma et al. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res. 2005, 65, 1479-1488. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology c-MET RTK class X; EC 2.7.10.1 ATP-competitive inhibitor of c-MET Chemical name (Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Parent CAS No. [658084-23-2] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
SU 11274Axon 1581 CAS [658084-23-2] MF C28H30ClN5O4S
Description
ATP-competitive and selective MET inhibitor; inhibition of the Met kinase activity by SU11274 led to time- and dose-dependent reduced cell growth and induced G1 cell cycle arrest and apoptosis
ATP-competitive inhibitor of c-MET
Chemical name(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Parent CAS No.[658084-23-2] |
| 产品资料 |
