产品名称

ARN 272

产品货号

Axon 2941 CAS [488793-85-7] MF C27H20N4O2MW 432.47 Purity: 98% Soluble in DMSO Recently added

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

ARN 272

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 2941

CAS [488793-85-7]

MF C27H20N4O2
MW 432.47

Purity: 98%
Soluble in DMSO

Recently added

ARN 272

Description

ARN 272 is a selective competitive antagonist of the interaction of anandamide with FAAH-like anandamide transporter (IC50 value of 1.8 µM). Moreover, ARN 272 prevents anandamide internalization in vitro, interrupts anandamide deactivation in vivo, and exerts profound analgesic effects in rodent models of nociceptive and inflammatory pain, which are mediated by CB1 cannabinoid receptors.

J Fu et al. A catalytically silent FAAH-1 variant drives anandamide transport in neurons. Nat Neurosci. 2011 Nov 20;15(1):64-9.

Selective inhibitor of FAAH-like anandamide transporter (FLAT)

Chemical name

4-(4-(4-Hydroxyphenyl)phthalazin-1-ylamino)-N-phenylbenzamide

Parent CAS No.

[488793-85-7]

产品资料