产品名称

Paroxetine hydrochloride

产品货号

Axon 1452 CAS [110429-35-1] MF C19H20FNO3.HClMW 365.83 Purity: 99% Optical purity: >98% ee Soluble in water and DMSO Description Selective serotonin reuptake inhibitor (SSRI); Paroxetine is used to treat major depression, obsessive-compulsive, panic, social anxiety, and generalised anxiety disorders in adult outpatients.Paroxetine has also been identified an inhibitor of GRK2 activity both in vitro and in living cells with up to 60-fold selectivity over other GRKs, and is capable of increasing myocardial contractility. References Certificates Categories Extra info S.R. Grimsley et al. Paroxetine, sertraline, and fluvoxamine: new selective serotonin reuptake inhibitors. Clin Pharm. 1992 Nov;11(11):930-57. D.M. Thal et al. Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility. ACS Chem Biol. 2012 Nov 16;7(11):1830-9. L. Weber et al. Paroxetine: a first for selective serotonin reuptake inhibitors - a new use: approved for vasomotor symptoms in postmenopausal women. Womens Health (Lond Engl). 2014 Mar;10(2):147-54. Certificate of Analysis Material Safety Data Sheet CNS SSRI Unclassified GRK SSRI Chemical name (S)-3-(Benzo[1,3]dioxol-5-yloxymethyl)-4-(4-fluoro-phenyl)-piperidine hydrochloride Parent CAS No. [61869-08-7] Order Size Unit Price Stock 10 mg €75.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Paroxetine hydrochloride

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1452

CAS [110429-35-1]

MF C19H20FNO3.HCl
MW 365.83

Purity: 99%
Optical purity: >98% ee
Soluble in water and DMSO

Paroxetine hydrochloride

Description

Selective serotonin reuptake inhibitor (SSRI); Paroxetine is used to treat major depression, obsessive-compulsive, panic, social anxiety, and generalised anxiety disorders in adult outpatients.
Paroxetine has also been identified an inhibitor of GRK2 activity both in vitro and in living cells with up to 60-fold selectivity over other GRKs, and is capable of increasing myocardial contractility.