产品名称

RAD51 inhibitor B02

产品货号

Axon 1911 CAS [1290541-46-6] MF C22H17N3OMW 339.39 Purity: 98% Soluble in DMSO Description Specific and cell-permeable RAD51 inhibitor; BO2 specifically inhibits the DNA strand exchange activity of human RAD51 (IC50 = 27.4 μM). It disrupts RAD51 binding to DNA, increasing cell sensitivity to DNA damage References Certificates Categories Extra info F Huang et al. Identification of Specific Inhibitors of Human RAD51 Recombinase Using High-Throughput Screening. ACS Chem. Biol. 2011, 6, 628-635. F Huang et al. Inhibition of Homologous Recombination in Human Cells by Targeting RAD51 Recombinase. J. Med. Chem. 2012, 55, 3011−3020 Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology RAD51 DNA-damage Response EC 3.1.22.4 Inhibitor of RAD51 Chemical name (E)-3-benzyl-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one Parent CAS No. [1290541-46-6] Order Size Unit Price Stock 10 mg €95.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

RAD51 inhibitor B02

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1911

CAS [1290541-46-6]

MF C22H17N3O
MW 339.39

Purity: 98%
Soluble in DMSO

RAD51 inhibitor B02

Description

Specific and cell-permeable RAD51 inhibitor; BO2 specifically inhibits the DNA strand exchange activity of human RAD51 (IC50 = 27.4 μM). It disrupts RAD51 binding to DNA, increasing cell sensitivity to DNA damage

F Huang et al. Identification of Specific Inhibitors of Human RAD51 Recombinase Using High-Throughput Screening. ACS Chem. Biol. 2011, 6, 628-635.

F Huang et al. Inhibition of Homologous Recombination in Human Cells by Targeting RAD51 Recombinase. J. Med. Chem. 2012, 55, 3011−3020

Inhibitor of RAD51

Chemical name

(E)-3-benzyl-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one

Parent CAS No.

[1290541-46-6]

产品资料