产品名称

CAIX Inhibitor S4

产品货号

Axon 2662 CAS [1330061-67-0] MF C15H17N3O4SMW 335.38 Purity: 99% Soluble in DMSO Description S4 is a carbonic anhydrase (CA) IX and XII inhibitor (Ki values 7 nM and 2 nM, respectively) and showed a positive response in in vitro assays for tumor cell migration and spreading. Moreover, CAIX inhibitor S4 effectively inhibited the spontaneous metastasis formation in MDA-MB-231 xenografts.

产品价格

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

CAIX Inhibitor S4

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2662

CAS [1330061-67-0]

MF C15H17N3O4S
MW 335.38

Purity: 99%
Soluble in DMSO

CAIX Inhibitor S4

Description

S4 is a carbonic anhydrase (CA) IX and XII inhibitor (Ki values 7 nM and 2 nM, respectively) and showed a positive response in in vitro assays for tumor cell migration and spreading. Moreover, CAIX inhibitor S4 effectively inhibited the spontaneous metastasis formation in MDA-MB-231 xenografts.

RG Gieling et al. Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts. J Med Chem. 2012 Jun 14;55(11):5591-600.

Carbonic anhydrase (CA) IX/XII inhibitor

Chemical name

4-(3-(3,5-Dimethylphenyl)ureido)phenyl sulfamate

Parent CAS No.

[1330061-67-0]

产品资料