产品名称 NCT-503
产品货号 Axon 2623 CAS [1916571-90-8] MF C20H23F3N4SMW 408.48 Purity: 98% Soluble in 0.1N HCl (aq) and DMSO Description Non-competitive PHGDH inhibitor (IC50 value 2.5 µM) that reduces the production of glucose-derived serine in cells and suppresses the growth of PHGDH-dependent cancer cells in culture and in orthotopic xenograft tumors. KEYWORDS: NCT-503 | supplier | PHGDH inhibitor | NCT503 | NCT 503 | CAS [1916571-90-8] | 3-phosphoglycerate | 3-PG | serine | cancer | NSCLC | phosphoglycerate dehydrogenase
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NCT-503

Based on 2 reference(s) in Google Scholar 9 10 2

Axon 2623

CAS [1916571-90-8]

MF C20H23F3N4S
MW 408.48

  • Purity: 98%
  • Soluble in 0.1N HCl (aq) and DMSO

NCT-503

Description

Non-competitive PHGDH inhibitor (IC50 value 2.5 µM) that reduces the production of glucose-derived serine in cells and suppresses the growth of PHGDH-dependent cancer cells in culture and in orthotopic xenograft tumors.

KEYWORDS: NCT-503 | supplier | PHGDH inhibitor | NCT503 | NCT 503 | CAS [1916571-90-8] | 3-phosphoglycerate | 3-PG | serine | cancer | NSCLC | phosphoglycerate dehydrogenase

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