产品名称

CX 4945 hydrochloride - Silmitasertib hydrochloride

产品货号

Axon 1965 CAS [N.A.] MF C19H12ClN3O2.HClMW 386.23 Purity: 98% Soluble in 0.1N NaOH(aq) and DMSO Description Orally available, potent and selective casein kinase 2 (CK2) inhibitor References Certificates Categories Extra info A Siddiqui-Jain et al. CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy. Cancer Res. 2010, 70, 10288-10298. AD Ferguson et al. Structural basis of CX-4945 binding to human protein kinase CK2. FEBS Lett. 2011, 585(1), 104-110. F Pierre et al. Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer. Mol. Cell Biochem. 2011, 356(1-2), 37-43. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell Wnt-β-Catenin EC 2.7.11.1 CK Inhibitor of Casein kinase 2 (CK2) Chemical name 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid hydrochloride Parent CAS No. [1009820-21-6] Order Size Unit Price Stock 5 mg €105.00 In Stock

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

CX 4945 hydrochloride - Silmitasertib hydrochloride

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1965

CAS [N.A.]

MF C19H12ClN3O2.HCl
MW 386.23

Purity: 98%
Soluble in 0.1N NaOH(aq) and DMSO

CX 4945 hydrochloride

Description

Orally available, potent and selective casein kinase 2 (CK2) inhibitor

A Siddiqui-Jain et al. CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy. Cancer Res. 2010, 70, 10288-10298.

AD Ferguson et al. Structural basis of CX-4945 binding to human protein kinase CK2. FEBS Lett. 2011, 585(1), 104-110.

F Pierre et al. Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer. Mol. Cell Biochem. 2011, 356(1-2), 37-43.

Inhibitor of Casein kinase 2 (CK2)

Chemical name

5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid hydrochloride

Parent CAS No.

[1009820-21-6]

产品资料