产品名称 | PF 4800567 |
产品货号 | Axon 1792 CAS [1188296-52-7] MF C17H18ClN5O2MW 359.81 Purity: 98% Soluble in DMSO Description Potent and selective casein kinase 1ε (Csnk1e or CK-1ε) inhibitor (IC50: 32 nM) with >20-fold selectivity over CK 1δ References Certificates Categories Extra info KM Walton et al. Selective inhibition of casein kinase 1 epsilon minimally alters circadian clock period. J. Pharmacol. Exp. Ther. 2009, 330(2), 430-439. QJ Meng et al. Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes. Proc. Natl. Acad. Sci. USA. 2010, 107(34), 15240-15245. CD Bryant et al. Csnk1e is a Genetic Regulator of Sensitivity to Psychostimulants and Opioids. Neuropsychopharmacology. 2011, 37, 1026-1035. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell Wnt-β-Catenin EC 2.7.11.1 CK Inhibitor of Casein kinase 1 (CK1-ε) Chemical name 3-((3-chlorophenoxy)methyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Parent CAS No. [1188296-52-7] Order Size Unit Price Stock 5 mg €95.00 In Stock |
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产品品牌 | axonmedchem |
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PF 4800567Axon 1792 CAS [1188296-52-7] MF C17H18ClN5O2
Description
Potent and selective casein kinase 1ε (Csnk1e or CK-1ε) inhibitor (IC50: 32 nM) with >20-fold selectivity over CK 1δ
Inhibitor of Casein kinase 1 (CK1-ε)
Chemical name3-((3-chlorophenoxy)methyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Parent CAS No.[1188296-52-7] |
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