| 产品名称 | PF 573228 |
| 产品货号 | Axon 1623 CAS [869288-64-2] MF C22H20F3N5O3SMW 491.49 Purity: 99% Soluble in DMSO Description Potent and selective inhibitor of focal adhesion kinase (FAK) with IC50 of 4 nM; Displays 50-250-fold selectivity over other protein kinases; a useful tool in functional study of non-receptor tyrosine inhibitor FAK in integrin-dependent signaling pathways in normal and cancer cells References Certificates Categories Extra info ML Jones et al. Characterization of a novel focal adhesion kinase inhibitor in human platelets. Biochem Biophys Res Commun. 2009, 389(1), 198-203. JK Slack-Davis et al. Cellular Characterization of a Novel Focal Adhesion Kinase Inhibitor. J. Biol. Chem. 2007, 282, 14845-14852. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology FAK EC 2.7.10.2 FAK inhibitor Chemical name 6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one Parent CAS No. [869288-64-2] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
PF 573228Axon 1623 CAS [869288-64-2] MF C22H20F3N5O3S
Description
Potent and selective inhibitor of focal adhesion kinase (FAK) with IC50 of 4 nM; Displays 50-250-fold selectivity over other protein kinases; a useful tool in functional study of non-receptor tyrosine inhibitor FAK in integrin-dependent signaling pathways in normal and cancer cells
FAK inhibitor
Chemical name6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one Parent CAS No.[869288-64-2] |
| 产品资料 |
