产品名称 | Kifunensine, (+)- - FR 900494 |
产品货号 | Axon 1730 CAS [109944-15-2] MF C8H12N2O6MW 232.19 Purity: 99% Soluble in water and DMSO Description A potent class I α-mannosidase inhibitor that inhibits the glycoprotein biosynthesis; inhibits both human endoplasmic reticulum α-mannosidase I and Golgi class I mannosidase with Ki value of 130 and 23 nM respectively References Certificates Categories Extra info H Kayakiri et al. Structure of kifunensine, a new immunomodulator isolated from an actinomycete. J. Org. Chem. 1989, 54(17), 4015-4016. AD Elbein et al. Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I. J. Biol. Chem. 1990, 265(26), 15599-15605. KW Hering et al. A practical synthesis of kifunensine analogues as inhibitors of endoplasmic reticulum alpha-mannosidase I. J Org Chem. 2005, 70(24), 9892-9904. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Diabetes & Metabolism Mannosidase-α EC 3.2.1.24 α-mannosidase inhibitor Chemical name (5R,6R,7S,8R,8aS)-6,7,8-trihydroxy-5-(hydroxymethyl)tetrahydroimidazo[1,2-a]pyridine-2,3(1H,5H)-dione Parent CAS No. [109944-15-2] Order Size Unit Price Stock 2 mg €120.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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Kifunensine, (+)- - FR 900494Axon 1730 CAS [109944-15-2] MF C8H12N2O6
Description
A potent class I α-mannosidase inhibitor that inhibits the glycoprotein biosynthesis; inhibits both human endoplasmic reticulum α-mannosidase I and Golgi class I mannosidase with Ki value of 130 and 23 nM respectively
α-mannosidase inhibitor
Chemical name(5R,6R,7S,8R,8aS)-6,7,8-trihydroxy-5-(hydroxymethyl)tetrahydroimidazo[1,2-a]pyridine-2,3(1H,5H)-dione Parent CAS No.[109944-15-2] |
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