产品名称

GTS 21 dihydrochloride - 3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride | DMXB | DMXB-A

产品货号

Axon 2860 CAS [156223-05-1] MF C19H20N2O2.2HClMW 381.30 Purity: 100% Soluble in water and DMSO Description Selective α7 nicotinic acetylcholine receptor (nAChR) partial agonist. At significantly higher concentrations GTS 21 behaves as an antagonist of α4β2 nAChRs and related type 3 5-HT receptors. KEYWORDS: GTS 21 dihydrochloride | supplier | α7 partial agonist | 3-(2 | 4-Dimethoxybenzylidene)-anabaseine dihydrochloride | DMXB | DMXB-A | GTS21 | GTS-21 | CAS [156223-05-1] | [148372-04-7] | Acetylcholine | nAChR | Agonist | Ion Channels | α4β2 | 5-HT3

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

GTS 21 dihydrochloride - 3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride | DMXB | DMXB-A

Based on 255 reference(s) in Google Scholar 8 10 255

Axon 2860

CAS [156223-05-1]

MF C19H20N2O2.2HCl
MW 381.30

Purity: 100%
Soluble in water and DMSO

GTS 21 dihydrochloride

Description

Selective α7 nicotinic acetylcholine receptor (nAChR) partial agonist. At significantly higher concentrations GTS 21 behaves as an antagonist of α4β2 nAChRs and related type 3 5-HT receptors.

KEYWORDS: GTS 21 dihydrochloride | supplier | α7 partial agonist | 3-(2 | 4-Dimethoxybenzylidene)-anabaseine dihydrochloride | DMXB | DMXB-A | GTS21 | GTS-21 | CAS [156223-05-1] | [148372-04-7] | Acetylcholine | nAChR | Agonist | Ion Channels | α4β2 | 5-HT3

DS Woodruff-Pak et al. A nicotinic agonist (GTS-21), eyeblink classical conditioning, and nicotinic receptor binding in rabbit brain. Brain Res. 1994 May 9;645(1-2):309-17.

W Kem et al. The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21): Chemical and Pharmacological Properties. Mar Drugs. 2006 Apr; 4(3): 255–273.

Selective α7 nicotinic acetylcholine receptor (nAChR) partial agonist

Chemical name

(E)-3-(3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydropyridin-2-yl)pyridine dihydrochloride

Parent CAS No.

[148372-04-7]

产品资料