产品名称

PHA 543613 dihydrochloride

产品货号

Axon 2109 CAS [478148-58-2] MF C15H17N3O2.2HClMW 344.24 Purity: 99% Optical purity: Optically pure Soluble in water and DMSO Description Potent and selective α7 nicotinic acetylcholine receptor (nAChR) agonist, which is characterized by rapid brain penetration and high oral bioavailability; a potential treatment of cognitive deficits in schizophrenia References Certificates Categories Extra info DG Wishka et al. Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive (...). J. Med. Chem. 2006, 49(14), 4425-4436. PR Krafft et al. PHA-543613 Preserves Blood–Brain Barrier Integrity After Intracerebral Hemorrhage in Mice. Stroke, 2013, 44(6), 1743-1747. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation nAChR Unclassified Pfizer Licensed Products nAChR agonist (α7 sub-unit selective) Chemical name (R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxamide dihydrochloride Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [478149-53-0] Order Size Unit Price Stock 10 mg €115.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

PHA 543613 dihydrochloride

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2109

CAS [478148-58-2]

MF C15H17N3O2.2HCl
MW 344.24

Purity: 99%
Optical purity: Optically pure
Soluble in water and DMSO

PHA 543613 dihydrochloride

Description

Potent and selective α7 nicotinic acetylcholine receptor (nAChR) agonist, which is characterized by rapid brain penetration and high oral bioavailability; a potential treatment of cognitive deficits in schizophrenia

DG Wishka et al. Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive (...). J. Med. Chem. 2006, 49(14), 4425-4436.

PR Krafft et al. PHA-543613 Preserves Blood–Brain Barrier Integrity After Intracerebral Hemorrhage in Mice. Stroke, 2013, 44(6), 1743-1747.

CNS Pain & Inflammation nAChR Unclassified Pfizer Licensed Products

nAChR agonist (α7 sub-unit selective)

Chemical name

(R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxamide dihydrochloride

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[478149-53-0]

产品资料