| 产品名称 | BX 430 |
| 产品货号 | Axon 2523 CAS [688309-70-8] MF C15H15Br2N3OMW 413.11 Purity: 99% Soluble in DMSO Description Noncompetitive, allosteric antagonist of human P2X4 receptor channels (IC50 value 0.54 μM as determined by Patch-clamp electrophysiology) with 10-100 fold selectivity over P2X1–P2X3, P2X5, and P2X7. A useful molecular probe to assess the specific role of P2X4 in inflammatory and neuropathic conditions, where ATP signaling has been shown to be dysfunctional. BX430 has no effect on mouse and rat P2X4Rs. KEYWORDS: BX 430 | supplier | P2X4 antagonist | BX430 | CAS [688309-70-8] | Calcium | P2X4 | Ion Channel | P2X | cation | inflammation | ATP | pain | purinoceptor | vasodilation | patch clamp | current |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
BX 430Axon 2523 CAS [688309-70-8] MF C15H15Br2N3O
DescriptionNoncompetitive, allosteric antagonist of human P2X4 receptor channels (IC50 value 0.54 μM as determined by Patch-clamp electrophysiology) with 10-100 fold selectivity over P2X1–P2X3, P2X5, and P2X7. A useful molecular probe to assess the specific role of P2X4 in inflammatory and neuropathic conditions, where ATP signaling has been shown to be dysfunctional. BX430 has no effect on mouse and rat P2X4Rs. KEYWORDS: BX 430 | supplier | P2X4 antagonist | BX430 | CAS [688309-70-8] | Calcium | P2X4 | Ion Channel | P2X | cation | inflammation | ATP | pain | purinoceptor | vasodilation | patch clamp | current
Allosteric antagonist of human P2X4 receptor channels
Chemical name1-(2,6-dibromo-4-isopropylphenyl)-3-(pyridin-3-yl)urea Parent CAS No.[688309-70-8] |
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