产品名称 GW 791343 hydrochloride
产品货号 Axon 1967 CAS [309712-55-8] MF C20H24F2N4O.3HClMW 483.81 Purity: 98% Soluble in water and DMSO Description P2X7 receptor antagonist; GW791343 was a negative allosteric modulator of the human P2X(7) receptor but at the rat P2X(7) receptor its predominant effect was positive allosteric modulation References Certificates Categories Extra info AD Michel et al. Negative and positive allosteric modulators of the P2X(7) receptor. Br. J. Pharmacol. 2008, 153(4), 737-750.    AD Michel et al. Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects. Br. J. Pharmacol. 2008, 155(5), 7387-7351.  Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology CNS Pain & Inflammation P2X7 Unclassified P2X7 receptor antagonist and allosteric modulator Chemical name 2-(3,4-difluorophenylamino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide trihydrochloride Parent CAS No. [309712-73-0] Inquire
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GW 791343 hydrochloride

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1967

CAS [309712-55-8]

MF C20H24F2N4O.3HCl
MW 483.81

  • Purity: 98%
  • Soluble in water and DMSO

GW 791343 hydrochloride

Description

P2X7 receptor antagonist; GW791343 was a negative allosteric modulator of the human P2X(7) receptor but at the rat P2X(7) receptor its predominant effect was positive allosteric modulation
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