产品名称 JNJ 47965567
产品货号 Axon 2890 CAS [1428327-31-4] MF C28H32N4O2SMW 488.64 Purity: 99% Soluble in DMSO Description Highly potent and brain penetrant P2X7 antagonist in human, rat, and mouse cell lines (pKi values of 7.9, 7.9 and 6.9 for human, rat, and human whole blood P2X7). Probe compound for the preclinical assessment of P2X7 blockade in animal models of neuro-inflammation. DMPK properties suitable for preclinical pharmacodynamics studies. Keywords: JNJ 47965567 | supplier | P2X7 antagonist | JNJ47965567 | JNJ-47965567 | CAS [1428327-31-4] | Non Selective (Cations) | P2X7 | Antagonist | Ion Channels | Brain Penetrant | Neuro-inflammation
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产品品牌 axonmedchem
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JNJ 47965567

Based on 6 reference(s) in Google Scholar 8 10 6

Axon 2890

CAS [1428327-31-4]

MF C28H32N4O2S
MW 488.64

  • Purity: 99%
  • Soluble in DMSO

JNJ 47965567

Description

Highly potent and brain penetrant P2X7 antagonist in human, rat, and mouse cell lines (pKi values of 7.9, 7.9 and 6.9 for human, rat, and human whole blood P2X7). Probe compound for the preclinical assessment of P2X7 blockade in animal models of neuro-inflammation. DMPK properties suitable for preclinical pharmacodynamics studies.

Keywords: JNJ 47965567 | supplier | P2X7 antagonist | JNJ47965567 | JNJ-47965567 | CAS [1428327-31-4] | Non Selective (Cations) | P2X7 | Antagonist | Ion Channels | Brain Penetrant | Neuro-inflammation

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