| 产品名称 | HMR 1031 |
| 产品货号 | Axon 1616 CAS [479203-71-9] MF C35H41N5O6MW 627.73 Purity: 98% Optical purity: Optically pure Soluble in DMSO and Ethanol Description Potent and specific integrin α4β1 or very late antigen 4 (VLA-4) receptor antagonist binding to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin; HMR1031 is a potential inhaled drug for the treatment of asthma References Certificates Categories Extra info B Shah et al. Effect of food on pharmacokinetics of an inhaled drug: a case study with a VLA-4 antagonist, HMR1031. J. Clin. Pharmacol. 2003, 43(12), 1341-9. S Rohatagi et al. Pharmacoscintigraphic comparison of HMR 1031, a VLA-4 antagonist, in healthy volunteers following delivery via a nebulizer and a dry powder inhaler. Am. J. Ther. 2004, 11(2), 103-113. Z Diamant et al. Effect of a very late antigen-4 receptor antagonist on allergen-induced airway responses and inflammation in asthma. Clin. Exp. Allergy 2005, 35(8), 1080–1087. Certificate of Analysis Material Safety Data Sheet Immunology Pain & Inflammation VLA-4 Receptor VCAM VLA-4 antagonist Chemical name (S)-3-((S)-2-(4,4-dimethyl-2,5-dioxo-3-(4-(3-o-tolylureido)benzyl)imidazolidin-1-yl)-4-methylpentanamido)-3-phenylpropanoic acid Parent CAS No. [479203-71-9] Order Size Unit Price Stock 2 mg €105.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
HMR 1031Axon 1616 CAS [479203-71-9] MF C35H41N5O6
Description
Potent and specific integrin α4β1 or very late antigen 4 (VLA-4) receptor antagonist binding to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin; HMR1031 is a potential inhaled drug for the treatment of asthma
VLA-4 antagonist
Chemical name(S)-3-((S)-2-(4,4-dimethyl-2,5-dioxo-3-(4-(3-o-tolylureido)benzyl)imidazolidin-1-yl)-4-methylpentanamido)-3-phenylpropanoic acid Parent CAS No.[479203-71-9] |
| 产品资料 |
