SR 49059 - Relcovaptan

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1256

CAS [150375-75-0]

MF C28H27Cl2N3O7S
MW 620.50

Purity: 98%
Optical purity: Optically pure
Soluble in DMSO

SR 49059

Description

Highly potent and selective vasopressin V1A receptor antagonist.

Steinwall et al. The effect of relcovaptan (SR 49059), an orally active vasopressin V1a receptor antagonist, on uterine contractions in preterm labor. Gynecol Endocrinol. 2005 20(2), 104-9.

Tahtaoui et al. Identification of the binding sites of the SR 49059 nonpeptide antagonist into the V1a vasopressin receptor using sulfydryl-reactive ligands and cysteine mutants as chemical sensors. J. Biol. Chem. 2003, 278, 40010.

Cardiovascular CNS A6 Vasopressin (V)

Vasopressin (V1A) antagonist

Chemical name

(S)-1-[(2R,3S)-5-Chloro-3-(2-chloro-phenyl)-1-(3,4-dimethoxy-benzenesulfonyl)-3-hydroxy-2,3-dihydro-1H-indole-2-carbonyl]-pyrrolidine-2-carboxylic acid amide

Parent CAS No.

[150375-75-0]

产品资料