| 产品名称 | Eltrombopag - SB 497115 |
| 产品货号 | Axon 1872 CAS [496775-61-2] MF C25H22N4O4MW 442.47 Purity: 98% Soluble in 0.1N NaOH(aq) and DMSO Description First-in-class, oral, nonpeptide thrombopoietin receptor (TpoR or MPL) agonist, which is developed as a treatment for thrombocytopenia of various etiologies. Eltrombopag activates TpoR signaling pathway and induces proliferation and differentiation in mammalian cells and cell lines References Certificates Categories Extra info JM Jenkins et al. Phase 1 clinical study of eltrombopag, an oral, nonpeptide thrombopoietin receptor agonist. Blood 2007, 109 (11), 4739–4741. JB Bussel et al. Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura. N. Engl. J. Med. 2007, 357(22), 2237-2247. CL Erickson‐Miller et al. Preclinical Activity of Eltrombopag (SB‐497115), an Oral, Nonpeptide Thrombopoietin Receptor Agonist. Stem Cells 2009, 27(2), 424-430. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell TPO (c-MPL) Unclassified Stem Cell Differentiator Thrombopoietin receptor (TpoR or c-MPL) agonist Chemical name (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxybiphenyl-3-carboxylic acid Parent CAS No. [496775-61-2] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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Eltrombopag - SB 497115Axon 1872 CAS [496775-61-2] MF C25H22N4O4
Description
First-in-class, oral, nonpeptide thrombopoietin receptor (TpoR or MPL) agonist, which is developed as a treatment for thrombocytopenia of various etiologies. Eltrombopag activates TpoR signaling pathway and induces proliferation and differentiation in mammalian cells and cell lines
Thrombopoietin receptor (TpoR or c-MPL) agonist
Chemical name(Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxybiphenyl-3-carboxylic acid Parent CAS No.[496775-61-2] |
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