产品名称

PD 123319 ditrifluoroacetate

产品货号

Axon 1276 CAS [136676-91-0] MF C31H32N4O3.2C2HF3O2MW 736.66 Purity: 99% Optical purity: Optically pure Soluble in water and DMSO Description Angiotensin II (AT-2) antagonist KEYWORDS: PD 123319 ditrifluoroacetate | supplier | AT2 antagonist | PD123319 | PD0123319 | CAS [136676-91-0] | [130663-39-7] | Angiotensin II | Antagonist | AT-II | cardiovascular | renal

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

PD 123319 ditrifluoroacetate

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1276

CAS [136676-91-0]

MF C31H32N4O3.2C2HF3O2
MW 736.66

Purity: 99%
Optical purity: Optically pure
Soluble in water and DMSO

PD 123319 ditrifluoroacetate

Description

Angiotensin II (AT-2) antagonist

KEYWORDS: PD 123319 ditrifluoroacetate | supplier | AT2 antagonist | PD123319 | PD0123319 | CAS [136676-91-0] | [130663-39-7] | Angiotensin II | Antagonist | AT-II | cardiovascular | renal

G Boulay et al. Modulation of angiotensin II binding affinity by allosteric interaction of polyvinyl sulfate with an intracellular domain of the DuP-753-sensitive angiotensin II receptor of bovine adrenal glomerulosa. Mol. Pharmacol. 1992, 41, 809.

Heller, J. et al. Effect of PD 123319, an AT-2 antagonist, on renal function of the anesthetized dog: comparison with EXP 3174, an AT-1 blocker. Kidney Blood Press Res. 1997;20(5):297-301.

Widdop R.E. et al. Central administration of PD 123319 or EXP-3174 inhibits effects of angiotensin II. Am. J. Physiol. 1993, 264, H117-125.

Keiser, J.A. et al. Renal hemodynamic and excretory responses to PD 123319 and losartan, nonpeptide AT1 and AT2 subtype-specific angiotensin II ligands. J. Pharmacol. Exp. Ther. 1992, 262(3), 1154-1160.

Cardiovascular Endocrinology A3 Angiotensin (AT)

AT2 antagonist

Chemical name

(S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenylacetyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid ditrifluoroacetate

Parent CAS No.

[130663-39-7]

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