SR 142948

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1255

CAS [184162-64-9]

MF C39H51N5O6
MW 685.85

Purity: 98%
Soluble in water

SR 142948

Description

Neurotensin (NT) receptor antagonist; orally active in vivo.

D Gully et al. Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist. J. Pharmacol. Exp. Ther. 1997, 280, 802.

SM Reynolds et al. Neurotensin antagonist acutely and robustly attenuates locomotion that accompanies stimulation of a neurotensin-containing pathway from rostrobasal forebrain to the ventral tegmental area. Eur. J. Neurosci. 2006, 24(1), 188-196.

CNS A7 Neurotensin (NT)

Neurotensin antagonist

Chemical name

2-[(5-(2,6-Dimethoxy-phenyl)-1-{4-[(3-dimethylamino-propyl)-methyl-carbamoyl]-2-isopropyl-phenyl}-1H-pyrazole-3-carbonyl)-amino]-adamantane-2-carboxylic acid

Parent CAS No.

[184162-64-9]

产品资料