产品名称

CCT 007093

产品货号

Axon 1821 CAS [176957-55-4] MF C15H12OS2MW 272.39 Purity: 99% Moderately soluble in DMSO Description An effective PPM1D inhibitor that selectively reduces viability of human tumour cell lines; apoptosis inducer References Certificates Categories Extra info S Rayter et al. A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D Oncogene. 2008, 27(8), 1036-1044. J Pärssinen et al. PPM1D silencing by RNA interference inhibits proliferation and induces apoptosis in breast cancer cell lines with wild-type p53. Cancer Gene Ther. 2008, 182(1), 33-39. DSP Tan et al. PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas. Clin. Cancer Res. 2009, 15, 2269. JA Bauer et al. RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells. Breast Cancer Res. 2010, 12(3), R41. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology PPM1D MAPK EC 3.1.3.16 Protein phosphatase 1D (PPM1D) inhibitor Chemical name (2E,5E)-2,5-bis(thiophen-2-ylmethylene)cyclopentanone Parent CAS No. [176957-55-4] Order Size Unit Price Stock 10 mg €95.00 In Stock

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现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

CCT 007093

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1821

CAS [176957-55-4]

MF C15H12OS2
MW 272.39

Purity: 99%
Moderately soluble in DMSO

CCT 007093

Description

An effective PPM1D inhibitor that selectively reduces viability of human tumour cell lines; apoptosis inducer

S Rayter et al. A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D Oncogene. 2008, 27(8), 1036-1044.

J Pärssinen et al. PPM1D silencing by RNA interference inhibits proliferation and induces apoptosis in breast cancer cell lines with wild-type p53. Cancer Gene Ther. 2008, 182(1), 33-39.

DSP Tan et al. PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas. Clin. Cancer Res. 2009, 15, 2269.

JA Bauer et al. RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells. Breast Cancer Res. 2010, 12(3), R41.

Protein phosphatase 1D (PPM1D) inhibitor

Chemical name

(2E,5E)-2,5-bis(thiophen-2-ylmethylene)cyclopentanone

Parent CAS No.

[176957-55-4]

产品资料