RAB7A Antibody is a Rabbit Polyclonal antibody against RAB7A. RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
| Target |
RAB7A |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC, IP |
| Recommended dilutions |
WB: 1/200 - 1/2000, IHC: 1/50 - 1/200, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
A synthetic peptide of human RAB7A. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 23 kDa
Observed MW: 23 kDa |
| Swiss Prot |
P51149
|
| GeneID |
7879
|
| Gene Symbol |
RAB7A |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |