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| Product Name | BCCIP, Recombinant, Human, aa1-314, His-Tag (BRCA2 and CDKN1A Interacting Protein) |
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| Description | Purity ~90% (SDS-PAGE). BCCIP was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Source: Recombinant protein corresponding to aa1-314 from human BCCIP, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~38.6kD (339aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_510868 |
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| Catalog # | 217969 |
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| Order / More Info | BCCIP, Recombinant, Human, aa1-314, His-Tag (BRCA2 and CDKN1A Interacting Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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