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| Product Name | B7-1/CD80 BioAssay™ ELISA Kit, Mouse |
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| Description | Sandwich ELISA quantitative detection kit for Mouse B7-1/CD80 in cell culture supernates and serum. The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain[1].The CD80 and CD86 (601020) genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types.[2] stated that B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4. The standard product used in this kit is recombinant |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 12519, SwissProt: Q00609 |
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| Catalog # | 143721 |
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| Order / More Info | B7-1/CD80 BioAssay™ ELISA Kit, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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