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| Product Name | TRAIL, 114-281aa, Human, E Coli |
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| Description | MW: 23 kDa (211 aa). Purity >95% by SDS-PAGE. TNF-related apoptosis-inducing ligand (TRAIL) belongs to the tumor necrosis factor (TNF) cytokine family and induces rapid apoptosis in a wide variety of tumor cell lines upon binding to the death-signalling receptors on the cell membrane. TRAIL binds to one of four receptors that have been identified in humans, including TRAIL-R1/DR4, TRAIL-R2/KILLER/DR5, TRAIL-R3/DcR1/TRID, and TRAIL-R4/DcR2/TRuNDD. Both DR4 and DR5 are pro-apoptotic receptors, whi |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Tumor necrosis factor (ligand) superfamily member 10; APO2L; Apo-2 ligand; Tumor necrosis factor ligand superfamily; member 10; TNFSF10; CD253; TL2; TRAIL; Tumor necrosis factor (ligand) superfamily; member 10; TNF-Related Apoptosis Inducing Ligand] |
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| Gene, Accession, CAS # | TRAIL, Gene ID: 8743, Accession: NP_003801 |
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| Catalog # | MBS203134 |
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| Order / More Info | TRAIL, 114-281aa, Human, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Janssen EM., et al. (2005). Nature. 434 (7029):88-93.; Deocaris CC., et al. (2007) Ann N Y Acad Sci. 1119:165-75; |
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