| 产品详情 |
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| Product Name | IPA-3 |
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| Description | Purity >95%. IPA-3 is a cell-permeable allosteric inhibitor of PAK1 (tha p21-activated kinase 1) that is non-competitive with respect to ATP binding (IC50 = 2.5 µM). It does not, however, inhibit the activity of PAK1 that has been pre-activated with Cdc42. IPA-3 binds covalently to the PAK1 regulatory domain (apparent Kd = 1.9 uM) and prevents binding to the upstream activator Cdc42. Potential anti-tumor agent. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1,1'-dithiobis-2-naphthalenol |
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| Gene, Accession, CAS # | CAS: 42521-82-4 |
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| Catalog # | LS-H4403 |
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| Price | |
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| Order / More Info | IPA-3 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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