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| Product Name | VAV1, Recombinant, Human, aa189-565, His-Tag (Proto-Oncogene Vav Isoform 1) |
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| Description | Purity ~85% (SDS-PAGE). Proto-oncogene vav isoform 1, also known as VAV1, is a member of the VAV gene family. The VAV1 proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. In addition, VAV1 contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of VAV1 is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages. Source: Recombinant protein corresponding to aa189-565 from human VAV1, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~46.8kD (400aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_005419 |
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| Catalog # | 218667 |
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| Order / More Info | VAV1, Recombinant, Human, aa189-565, His-Tag (Proto-Oncogene Vav Isoform 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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