产品详情 |
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Product Name | PYR-41 |
Description | Cell-permeable. An irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 µM). Blocks ubiquitylation and prevents ubiquitin-mediated proteasomal degradation. Inhibits NF-κB activation, blocks degradation of p53, increases p21 levels and induces apoptosis in vitro. Also causes an increase in sumoylation of proteins. MW: 371.3. Purity ≥98% by TLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[4-[(5-Nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]benzoic acid ethyl ester |
Gene, Accession, CAS # | CAS: 418805-02-4 |
Catalog # | 1925-25 |
Price | |
Order / More Info | PYR-41 from BIOVISION, INC. |
Product Specific References | n/a |
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