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| Product Name | p70S6K, Recombinant, Human, His-tag |
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| Description | Purified (~70-90%). p70S6K is responsible for the phosphorylation of 40S ribosomal protein S6 and is ubiquitously expressed in human adult tissues. p70S6K is activated by serum stimulation and this activation is inhibited by wortmannin and rapamycin. p70S6k activity undergoes changes in the cell cycle and increases 20-fold in G1 cells released from G0. p70S6K activation requires sequential phosphorylations at proline-directed residues in the putative autoinhibitory pseudosubstrate domain, as well as threonine 389 a site phosphorylated by phosphoinositide-dependent kinase 1 (PDK-1). Source: Recombinant protein corresponding to human p70S6K, fused to His-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~76kD Specific Activity: 78nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | p70S6K, Recombinant, Human, His-Tag (Ribosomal Protein S6 Kinase beta-1, 70kD Ribosomal Protein S6 Kinase 1, Ribosomal Protein S6 Kinase I, Serine/Threonine-protein Kinase 14A, S6K, PS6K, S6K1, STK14A, RPS6KB1, p70-Alpha, p70(S6K)-Alpha) |
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| Gene, Accession, CAS # | Accession: NM_003161 |
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| Catalog # | 500332 |
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| Order / More Info | p70S6K, Recombinant, Human, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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